News and Updates
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- 細胞死関連プロテインキナーゼによる解糖系の制御Death-associated protein kinase increases glycolytic rate through binding and activation of pyruvate kinase.
- ピルビン酸キナーゼM2アイソザイムとHIF-1の関係Pyruvate kinase M2 regulates glucose metabolism by functioning as a coactivator for hypoxia-inducible factor 1 in cancer cells.
- ピルビン酸キナーゼM2アイソザイムのアセチル化による調節Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth.
- ピルビン酸キナーゼM2アイソザイムとミトコンドリア呼吸の関連性Enhancing mitochondrial respiration suppresses tumor promoter TPA-induced PKM2 expression and cell transformation in skin epidermal JB6 cells.
- ピルビン酸キナーゼM2アイソザイムとHIF-1のポジティブフィードバック制御Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1.
