TOP - HMT METABOLOMICS
All livings thing are comprised of a variety of chemical compounds or metabolites, that are produced, degraded, absorbed and secreted by our cells. Metabolomics, the study of these compounds, is an established biochemical approach to profile global changes of metabolites, providing understanding of dysfunction and adaption of biological systems.
A Piece of System Biology
Metabolomics targets thousands of metabolites in cells and biological samples. From the massive volume of the data, statistical and multivariate analyses extract “Biomarkers” as key features in biological pathways and mechanisms of action. Biomarkers can provide novel insights in metabolic pathways and together with genomic, transcriptomic, and proteomic data, a complete picture or systems approach is achieved to understanding biology and disease.
The A-B-C’s of A New Discovery
Metabolomics can be achieved with a combination of three key technologies – Analytical chemistry, Biology and Computer science. High-performance Analytical methods need to be operated with documented SOPs and process requirements to produce high-quality, accurate, and reproducible analyses. Biologists provide research plans, sample analyses and interpretations deriving novel hypothesis based on well validated results. An enormous amount of metabolome data will be processed by Computer programs that extract intrinsic characteristics by using statistical and pathway based analysis.
Improving Quality of Life
Metabolomics leads to innovations in medical care by revealing novel aspects of dysregulations in our body. Novel biomarkers help development of pharmaceutical, diagnostic and medical cares in fields such as, cancer, diabetes, cardiovascular disease, immune disease and neuroscience. The rediscoveries modifying classical theories contributes to the improvement of advanced technologies such as oncotherapy, precision medicine and regenerative medicine. Metabolomics is providing new perspectives of uncontrolled diseases that will lead to improvements of our quality of life.
Technology for Innovations
The number of publications involving Metabolomics has increased 10-fold in the past 10 years. This field is spreading in a variety of industries including agriculture, food science, bioprocessing, fermentation and more. Now, metabolomics is used in all over the world and provided by academic and business laboratories. Over the past 10 years, we have supported many diverse organizations looking for innovative ways to achieve their goals in product quality, research and development.