Visualization of metabolic pathways allows for a more in depth understanding of metabolomic data. Our services and data analysis enables you to find meaningful mechanistic changes. Please use our interactive pathway map on the left to learn more about current research in the field of metabolomics.
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The demand for metabolomics is increasing in a variety of research areas including oncology, immunology, cardiology etc., as the data provides conclusive links between genotype and phenotype. Our analysis platform covers a majority of primary metabolic pathways which are engaged and modulated in a wide range of impactive diseases, some of which are highlighted below. Metabolomics has played a major role in their diagnosis and treatment.
Recent studies continue to reveal new aspects of cancer metabolism, which supplements the basic Warburg hypothesis that states cancer cells are glycolytically dependent. Our partners have revealed links to cancer metabolism among serine, glycine, glutamine and arginine metabolic pathways, to name a few.
Metabolomics identifies multiple synthetic lethal therapies for ASS1 deficient cancers
Cancer metabolism under Hypoxia
Myc-driven glycolysis is a therapeutic target in glioblastoma
The immune cell, such as T-cell, shows dynamic changes in energetic metabolism during the cellular proliferation and differentiation. The characterization of intracellular metabolism is the key to understand immune dysfunctions.
The dysfunction in mitochondria causes a variety of diseases including cardiomyopathy. The assessment of oxidative phosphorylation activity enables to provide novel criteria for myocardial functions.