Metabolomics, a comprehensive analysis of small molecular compounds in biological samples, is a powerful tool because almost all biological phenomena result in changes in an organismal or cellular metabolic state. However, grasping global changes in metabolism is not easy because it requires the precise measurement of these compounds with a variety of physical and chemical properties.
We provide a broad profiling of hydrophilic metabolites with our Capillary Electrophoresis Mass Spectrometric (CE-MS) platforms, adding additional hydrophobic metabolites with our LC-MS platform to capture a wide variety of metabolites and pathways.
Our analysis provides comprehensive and quantitative profiling and with optimized protocols, we can analyze metabolites from a variety of samples and organisms.
Global metabolic profiling targets more than 1,200 metabolites involved in primary and secondary metabolism pathways shared by many organisms.
Our unique CE-MS analysis provides accurate and robust profiling including the metabolism of sugars, amino acids, nucleotides, lipids, and stress response biomarkers. Together with CE-MS, LC-MS based lipidomics provides changes in lipid turnover engaged in cellular energy and signaling pathways.
This package is useful for researchers in a variety of areas and sample species.
Our Advanced profiling mode covers the complete metabolome including unknown metabolites observed in CE-TOFMS data analysis. In addition to cell derived metabolites, peptides, exogenous compounds, and disease specific novel compounds will be detected and screened as biomarkers for disease or bioprocessing.
All projects are performed under QC conditions based on established SOPs and experience of over 10 years of operation. Together with multivariate and statistical analysis, this package is the ultimate tool for biomarker screening and metabolism based profiling.