We provide advanced metabolomic services covering both global profiling and quantitative targeted analyses. Our unique technology, Capillary Electrophoresis Mass Spectrometry (CE-MS), provides high quality sensitive quantitative metabolic profiling for a wide range of metabolism including bioenergetics, protein and DNA turnover, stress response, and bioprocessing. With our established technology, the experience of over 10 years of operations along with our experienced biochemists, we can advance your research goals.
HMT Can Provide Accurate Quantitative Data in 4 to 6 Weeks.
Recommended Experiment Design Would Include:
Global profiling provides a comprehensive analysis of the metabolic pool based on CE-MS and LC-MS. It covers more than 1,200 compounds involved in sugar, amino acids, lipid and hormone metabolism. Furthermore, we provide an advanced profiling platform allowing for the identification of un-known metabolites for biomarker discovery.
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Basic / Dual Scan - Multipurpose Profiling for Global Metabolism
Targeted analysis provides accurate quantitation of metabolites engaged in pathways of bioenergetics, cellular proliferation, stress response, and protein turnover. It will provide an intuitive understanding of metabolic changes based on our biochemical parameters representing intracellular metabolic status. We also provide isotope labeling analysis for the determination of metabolic flux.
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C-SCOPE - Quantitative Analysis of Central Energy Metabolism
F-SCOPE - 13C Isotope Labeling Analysis
|Global Profiling||Targeted Analysis|
|Advanced Scan||Basic Scan||Dual Scan||C-SCOPE||F-SCOPE|
|Target||+Unknown*1 metabolites||Primary metabolic pathways||+Lipid metabolism||Central energetic metabolism||Carbon & Amino acid turn-over|
|Coverage||Central carbon metabolism||✔||✔||✔||✔||✔|
|Protein & DNA
|Other primary metabolism||✔||✔||✔|
|Our Library||1,500 +
+ 30 parameters*2
|Reporting value||Relative values
(Quantitation option is available)
|Absolute quantitation||Relative values
+ Quantitation OP
|Data analysis||+ Marker Screening||Statistical analysis, PCA, HCA, Pathway mapping
(*depending on study design)
|Applications||Biomarker||Biomarker / Fingerprinting / MOA||MOA|