The most comprehensive plan that measures lipophilic metabolites, in addition to hydrophilic and ionic metabolites.

Capable of identifying more than 1,300 metabolites

Coverage of over 1,000 hydrophilic and ionic metabolites, and 300 lipophilic metabolites

Metabolic pathway mapping, PCA, and HCA with heat map are also included

Dual Scan provides a comprehensive analysis of over 1,000 hydrophilic and ionic metabolites, as well as over 300 lipophilic metabolites.
It covers many metabolites such as sugar phosphates, amino acids, nucleic acids, organic acids, vitamins, short/medium chain fatty acids, dipeptides, fatty acids, acylcarnitines, bile acids, steroid derivatives, etc. Hence, Dual Scan is ideal for non-targeted profiling of a wide range of metabolites.

Results will be summarized in a study report, with an Excel file containing numerical data.

The report will include the following:

  • Detected peak values (relative area values)
  • Results of comparison between groups using relative area values
  • Principal component analysis (PCA) and heat map of hierarchical clustering analysis (HCA) results
  • Pathway maps drawn based on measurement results that include central carbon metabolism and amino acid metabolism

Analysis Details

Plan Overview HMT’s CE-MS platform, which combines capillary electrophoresis (CE) and mass spectrometry (MS), and LC-MS platforms provide comprehensive analysis of metabolites with various physical properties i.e., metabolomics. The combination of CE, which excels in the separation of hydrophilic and ionic metabolites, and LC, which is suitable for the separation of lipophilic and neutral metabolites, enables the detection of a wide range of metabolites.
Main Applications Understanding the metabolic changes in primary metabolism that exist in many species.
Search for new networks of metabolites and pathways.
Target Metabolites Approximately 1,000 hydrophilic and ionic metabolites and 300 lipophilic metabolites, including sugar phosphates, amino acids, nucleic acids, organic acids, vitamins, fatty acids, acylcarnitines, bile acids, steroid derivatives, etc.
Sample Type Most types of biological specimens
Platform CE-TOFMS
LC-TOFMS
Standard Turnaround Time Within 60 days

Frequently Asked Questions

What sample types can be analyzed?

We analyze all kinds of samples at HMT. However, please contact us first as certain sample types may be subject to Japan’s customs restrictions.

 

Is there a minimum order requirement?

We accept a minimum of one sample for Dual Scan. Bulk discount is available depending on the number of samples. Please contact us for details.

 

Can you quantify the concentration of metabolites?

HMT’s 110 or 353 selected metabolites are quantifiable with single-point calibration. These metabolites can be found in our Annotation List, which is available here.
Please contact us if you would like to quantify other metabolites.

 

What are the metabolites covered by Dual Scan?

Please refer to our Annotation List for the lineup of measurable metabolites.

 

How much does the analysis cost?

The price will vary depending on the test scale, number of samples and inclusion of any optional analyses. Please contact your local distributor. If your local distributor is not listed here, please contact us.

 

How do I request for analysis?

Please refer to our Service Flow.

 

Please check here for information on the required sample volume, study design and report.


Service Leaflet : Dual Scan

For more detailed information, download our Service Leaflet from the following page:

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